The Difference in Mouthwash Side Effects of Persica and Chlorhexidine for Preventing Ventilator-induced Pneumonia among Patients Admitted to the Intensive Care Unit

Background: Pneumonia is a common cause of morbidity and mortality in ICU patients under mechanical ventilation. In recent years the use herbal mouthwashes, due to antimicrobial effects fewer side effects, has been studied reducing incidence ventilator-associated pneumonia (VAP). this study, effect Persica mouthwash prevention VAP was compared with chlorhexidine. Methods: This study double-blind, randomized clinical trial among Fifty were divided into two groups, control group used 10 ml Chlorhexidine 2.0%, intervention 10cc as mouthwash. The pneumonia, mortality, length hospital stays, ventilation duration, CPIS (Clinical Pulmonary Infection Score), SOFA (sequential organ failure assessment) score complications evaluated groups. Results: score, groups not significantly different. Length stay duration also different p>0.05. Side chlorhexidine more often than (44% vs . 8%) p=0.008. Conclusion: early no baseline did differ At same time, caused by less. Clinical Trial Registrations No.: RCT2017022032676N1.